Picamilon and Mood Enhancement

Picamilon is a combination of niacin and GABA developed in the Soviet Union in 1969. It is broken down in the body into its constituents, and is used as a mood enhancer. Both niacin and GABA are known to help improve mood, and taking picamilon can provide a positive outlook and reduce anxiety.

Niacin, GABA, and Mood

In picamilon, niacin is utilized as a carrier to distribute GABA throughout the body. GABA, or gamma aminobutyric acid, is a neurotransmitter that regulates the nervous system. Though GABA alone cannot cross the blood-brain barrier, when it is prepared with niacin it can cross the barrier and activate GABA receptors in the brain. The GABA produces a calming effect,picamilon is a blend of niacin and gaba that can help mood and the carrier niacin also acts as a vasodilator, which increases blood flow to the brain and can help reduce headaches [1]. Picamilon has been shown in studies on cats to have a tranquilizing effect and reduce bodily response to stress, but it does not cause drowsiness [2]. In fact, picamilon has stimulating as well as tranquilizing effects. It improves recovery time after physical work, and also helps with memory and focus.

Benefits of Picamilon

Picamilon works as a mood-enhancing supplement because it reduces blood pressure. It also works as a nootropic by benefiting the brain and nervous system. It works quickly, passing through the blood-brain barrier and lasting longer in the body than GABA or niacin alone would. It has a calming effect without making the user drowsy or lethargic, and can also help reduce headaches and improve mental focus. Picamilon can provide relief from everyday stress as well as provide a mental boost without the need for caffeine or other stimulants.

Picamilon Dosage

As a supplement, picamilon is available in powder form and in capsules. The recommended picamilon dosage is between 50 and 100 mg per day. Higher amounts of picamilon will provide more of a mentally stimulating effect, while lower dosages will act more as a tranquilizer. It is best to try different levels and find what works best for the individual. Adding picamilon to a daily regimen is easy and can help reduce stress and anxiety and promote a positive mood all day.


1. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC548511/
2. http://www.lef.org/magazine/mag97/july-lbn297.htm

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